I wanna say DoA has always impressed me. You've created characters who have to confront each other's beliefs just like people do in real life. People may think you're using religion as an easy punchline because they're not used to seeing anything else- they expect a webcomic to either mock religion, pretend religion doesn't exist, or be outright religious. But no one lives in a hermetic world like that. DoA is almost a 'how to deal with the fact that people we like all think differently' guide.
Which is weird, because I am still anti-social as crap! WHERE IS THIS KNOWLEDGE MANIFESTING FROM